This is the Debian README for tweet-django

Before using tweet-django, please configure it. The configuration file is located in /etc/tweet-django/settings.py
You will probably need to edit the following settings:

ALLOWED_HOSTS: Add the host name your web server is reachable as
LANGUAGE_CODE, TIME_ZONE, etc: Edit to taste
TWEET_OAUTH_*: Please register your application instance with Twitter and fill in the credentials here
TWEET_MAPQUEST_API_KEY: Please register with MapQuest and fill in the API key here

Also have a look at /etc/apache2/conf-enabled/tweet-django. You may want to change the URL path the
application is made available at (by default /tweet-django/tweet/), or have the application only
available in one (or more) virtual hosts, or add an extra alias.

After configuring, you will need to (re)start the streaming tweet daemon:
# systemctl restart tweet-django
and the Apache web server:
# systemctl restart apache2
